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非哺乳期乳腺炎是一种慢性炎症,多发于中青年女性,近年来发病率逐渐上升,其发病机制仍不明确,缺乏精准的治疗措施。目前研究认为主要是自身免疫、激素水平和微生物等因素相互作用的结果,如Th/Treg细胞失衡诱导IL-2、IL-17、IFN-γ等细胞因子变化;机体催乳素水平增高;乳房组织及脓液中特殊类型棒状杆菌激活免疫细胞及其外毒素作用等。笔者就非哺乳期乳腺炎病因及发病机制予以综述,为进一步明确非哺乳期乳腺炎的发生发展提供重要的理论依据,从而制定个体化有效的临床治疗方案及预防措施。
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基本信息:
DOI:
中图分类号:R655.8
引用信息:
[1]路晓阳,冯景,周毅.非哺乳期乳腺炎病因及发病机制研究进展[J].中国现代普通外科进展,2023,26(01):45-48+67.
基金信息:
黑龙江省自然科学基金项目(YQ202011012)